viral vector manufacturing

ABL is a biotech corporation headquartered in Rockville, MD, providing contract manufacturing and laboratory research services to advance vaccines and therapies from clinical development to the commercial market. It is a CDMO focused on viral vector manufacturing with GMP facilities in Rockville, MD and in Strasbourg and Lyon, France (ABL Europe). ABL has 30+ years of viral-vector development and GMP production experience.

analytical testingaseptic fill/finishassay development and qualificationcell and virus bankingGMP manufacturingimmunoassaysprocess developmentQC release testingscale upupstream and downstream process development

Andelyn Biosciences is a full-service cell and gene therapy CDMO based in Columbus, OH, spun off from Nationwide Children's Hospital in January 2020. It provides viral vector and plasmid manufacturing, process development, laboratory services, technology transfer, and its AAV Curator® Platform from preclinical to commercial cGMP production.

AAV Curator® Platformanalytical developmentcGMP manufacturingplasmid manufacturingprocess developmentquality controltechnology transfer

Cirsium Biosciences develops viral vector production methods and systems using whole plants as bioreactors, aiming to democratize gene therapy through transformative manufacturing methods. The company was founded in 2019 (formerly known as Vecprobio, Inc.) and is based in San Diego, CA. Its plant-based platform uses a linear scale-out production model and controlled environment agriculture to produce recombinant AAV vectors.

controlled environment agriculture (CEA)downstream processingfermentationlinear scale-out productionrecombinant AAV vector productionwhole-plant bioreactor production