strain engineering

Arzeda is a protein design company that uses its Intelligent Protein Design Technology™, combining physics-based protein design and AI algorithms, to create and manufacture new designer proteins and enzymes. Founded in 2009 by David Baker, Alexandre Zanghellini, and colleagues from the Institute for Protein Design at the University of Washington, it develops products for food & nutrition, home & personal care, advanced materials, and pharma.

AI-driven protein designcomputational protein designdownstream processingfermentationformulation developmentmachine learningmanufacturing scale-upphysics-based protein design

AsimicA is a B2B strain engineering company launched in November 2018 as a spin-off from a University research project and incorporated in 2020. It develops Microbial Stem Cell Technology (MiST), which gives microbes stem-cell-like properties so they divide asymmetrically, repopulating biofactories with young, productive microbes during fermentation batches to increase bioreactor productivity and batch lifetime.

fermentation process improvementmicrobial stem cell technology

BiomEdit is an animal health biotechnology company developing Programmable Veterinary Biologics, beneficial bacteria engineered to perform specific biological functions in livestock and pets. Located inside the laboratory facilities of the Indiana Biosciences Research Institute in Indianapolis, Indiana, the company applies microbial discovery, strain engineering, computational biology, and product development to address infectious disease, chronic disease, and sustainability challenges in animal health.

AI/MLcommercializationcomputational biologymicrobial discoveryproduct developmentRegulatory Affairssequencing

Bluestem Biosciences has engineered a proprietary industrial fermentation process that converts sugars from American corn into high-purity 3-hydroxypropionic acid (3-HP) using a specially developed strain of yeast. The platform is designed to retrofit into existing American bioethanol facilities, utilizing over 90% of existing infrastructure to produce platform chemicals at commercial scale.

Ag Bio productionindustrial fermentationmetabolic engineeringretrofitting bioethanol facilities

Cellibre uses biology as a manufacturing technology, employing nature's machinery to make products more sustainably. The company works in strain engineering, biochemistry and protein engineering, and precision fermentation, designing microbes that make products and moving production from farms to fermentation.

analytical chemistrybiochemistrybioprocessingprecision fermentationprotein engineering

REIMAGINING INDUSTRIAL FERMENTATIONSmall organisms.Extraordinarypossibilities.We’re developing a new approach to fermentation, starting with how microbes breathe.Explore our technology↗Discover our applications MICROBIAL SCIENCE / INDUSTRIAL POSSIBILITYLATEST NEWSIzote awarded NSF SBIR Phase I funding↗THE IZOTE APPROACHRethinking whatfermentation can do.Oxygen delivery is a major constraint in industrial fermentation. We’re developing a different way for microbes to breathe, with manufacturing in mind from the start.01A different way to breathe Our platform is designed to help microbes grow without depending on a continuous supply of oxygen.Explore the science ↗02Built for manufacturing Using a dissolved alternative to oxygen could reduce the air and mixing required during fermentation.See what this could enable ↗03Molecules that matter We develop fermentation routes to specialty.

fermentation process developmentmicrobial physiologyprocess engineering