synthetic organic chemistry

Acheminall Corporation works on drug discovery and development of small molecule therapeutics to treat schistosomiasis and breast cancer. Its work includes computer-aided drug design, photoreactive chemical probes, target engagement, small molecule drug design, synthetic organic chemistry, and virtual screening.

computer-aided drug designphotoreactive chemical probessmall molecule drug designtarget engagementvirtual screening

Crestone, Inc. is a clinical stage biopharmaceutical and biotech company in Boulder, Colorado focused on inventing and developing novel mechanism of action small molecule drugs for serious bacterial infections. Its pipeline includes antibacterial agents targeting C. difficile infection, resistant Gram-positive infections such as MRSA and VRE, and nontuberculous mycobacterial (NTM) disease and tuberculosis.

analytical chemistryanalytical (LC-MS, NMR)antimicrobial susceptibility testing according to CLSI guidelinesbiochemistrycell biologymedicinal chemistry (synthesis, analog design)microbiological profilingMicrobiologypharmacologyprocess chemistryScale up

Key Organics Limited is a provider of chemistry services, analytical services and BIONET products to the global life science industries, including pharmaceutical, agrochemical and biotechnology sectors. The company offers over 344,000 products, with over 90% in stock, and provides custom synthesis, process development and scale-up, targeted protein degradation, fragment services, compound procurement, consultancy and analytical services.

asymmetric synthesiscarbonylationscustom synthesisGC method developmentheterocyclic chemistryhigh pressure reactionsHPLChydrogenationsmicrowave synthesisNMRparallel synthesisprocess developmentpro-drug synthesisScale upstable labelled compounds