process chemistry

AAPharmaSyn is a US-based contract research organization (CRO) providing synthetic and medicinal chemistry services to pharmaceutical and biotechnology clients since 2006. Services include custom chemical synthesis, medicinal chemistry, custom lipid synthesis, stable isotope labeled compounds, process research and development, and project management support.

analytical supportasymmetric synthesischiral resolutionconjugation chemistrycustom synthesisisotope labelinglipid synthesismedicinal chemistrymulti-step synthesispurification and characterizationroute scoutingscale-up/pilot synthesis

Adesis is a contract development and manufacturing organization (CDMO) that partners with pharmaceutical, medical device, and specialty materials companies to develop, scale, and commercialize complex chemistry from early discovery through manufacturing. It operates US facilities in Delaware and a 17-acre site in County Clare, Ireland, and is a subsidiary of Universal Display Corporation (Nasdaq OLED).

analytical chemistrychiral separationcustom peptide synthesisdeuterationdiscovery chemistryflow chemistryGC-MSHPLC-MSNMRScale upsolid-phase synthesissolution-phase synthesisspecialty manufacturing

Aralez Bio is a biotechnology company that delivers noncanonical amino acids using a pioneering enzyme platform powered by water and biocatalysis. The company produces noncanonical amino acids at commercial scale, including multi-kg batches at its Berkeley, CA plant, and emphasizes greener, sustainable chemistry for therapeutic development.

biocatalysisdirected evolutionenzymatic synthesisQA/QCscale-up manufacturing

Chem-Master International, Inc. is a research, development, and manufacturing company founded in 1994 that specializes in contract projects, providing custom chemical synthesis, process development, and chemical research services to pharmaceutical companies, biotechnology organizations, drug discovery groups, and academic institutions in the U.S. and Europe.

analytical methods development and validationcGMP synthesischemical researchcontract synthesiscustom synthesisFT-IRGCHPLCLC/MSNMRprocess developmentroute scouting and selectionScale up

Crestone, Inc. is a clinical stage biopharmaceutical and biotech company in Boulder, Colorado focused on inventing and developing novel mechanism of action small molecule drugs for serious bacterial infections. Its pipeline includes antibacterial agents targeting C. difficile infection, resistant Gram-positive infections such as MRSA and VRE, and nontuberculous mycobacterial (NTM) disease and tuberculosis.

analytical chemistryanalytical (LC-MS, NMR)antimicrobial susceptibility testing according to CLSI guidelinesbiochemistrycell biologymedicinal chemistry (synthesis, analog design)microbiological profilingMicrobiologypharmacologyScale upsynthetic organic chemistry