molecular biology

Ag-Defense Systems focuses on protecting America's food from farm to table. The company works in molecular biology and nucleic acid technology, as well as electrical, mechanical, and program engineering, and provides prototype development, fabrication, and evaluation.

electrical engineeringevaluationfabricationmechanical engineeringnucleic acid technologyprogram engineeringprototype development

Agragene, Inc. is a sustainable agricultural technology company founded in 2017 and based in St. Louis, Missouri. It develops precision-guided sterilization and sex selection of insects for agricultural use, including its Precision-Guided Sterile Insect Technology (pgSIT) that produces sterile male insects for pest control. Its first commercial product, KNOCKOUT SWD, targets spotted wing drosophila in berries and cherries, with a research pipeline extending to livestock pests such as the New World screwworm.

biological pest controlentomology researchprecision-guided sterilization and sex selection of insects

Annagen BioTech LLC is a group of scientists investigating the mechanism of aging and translating scientific data into products. They developed a facial cream with a patent-pending formula under the trade name The American Mollusk Beauty, and are close to launching it for commercial distribution. They also conduct R&D on a non-PCR based in vitro diagnostic system (NIDS) for mRNA detection and on small molecules for wound healing.

aging researchdiagnostic assay developmentdrug developmentR&Dtissue culture

Astria Biosciences, Inc is a Pittsburgh-based startup company developing diagnostic and therapeutic solutions for cerebrovascular disease. It is developing a blood-based diagnostic test to detect and risk-stratify cerebral aneurysms as well as molecular-based therapies to combat this disease. Its work is supported by NSF SBIR Phase I # 2335396.

diagnosticshigh-throughput analysistherapeutics development

Bay Genomics, LLC is a Berkeley, CA based laboratory providing technology development for the life sciences. It helps clients develop cell models, genetic sequence analysis, cell culture work, drug testing, and proof-of-concept device development, and offers expertise in molecular biology, genetics, gene therapy, microscopy, histology, neuroscience, tissue culture, biochemistry, immunology, animal models of disease, bioinformatics, virus design, gene arrays, and sequencing. It is registered with SAM to subcontract on federal contracts and has experience

3D printinganimal models of diseasebiochemistryBioinformaticscomputer-aided designgene arraysgene therapygeneticshistologyimmunologyMicroscopyneurosciencePCB designphysiologypromoter bashingsequencingsolderingtissue culturevirus design

Bio-Synthesis is a U.S.-based custom synthesis and chemistry development CDMO supporting nucleic acids, peptides, bioconjugation, molecular biology services, analytical testing, scale-up, and therapeutic development workflows. Founded in 1984, it operates a 75,000 sq. ft. facility in Lewisville, Texas, with cGMP-aligned manufacturing from preclinical to commercial scale.

analytical testingbioconjugationcGMP manufacturingHPLC purificationmass spectrometry (MALDI-TOF, LC-MS, ESI)oligonucleotide synthesisPAGE purificationpeptide synthesisscale-up manufacturingtangential-flow filtrationUV spectrophotometry

The Istituto di Ricerca Genetica e Biomedica (IRGB) is a research institute of the Consiglio Nazionale delle Ricerche (CNR), with main offices in Monserrato (Cagliari) and secondary sites in Lanusei, Milan and Sassari. It conducts basic and translational research in genetics and biomedical genomics, including rare genetic diseases, cardiovascular diseases, regenerative medicine and oncology.

bioinformatics/high-performance computingcell biologycytogeneticsGenomicsgenotypingliquid biopsymolecular diagnosticsNGS sequencingproteomics

DermaXon is a Montana-based drug discovery and development company founded in 2013 providing first-in-class drug candidates. It targets the brain-skin connection to discover and develop novel therapeutic strategies to treat life-threatening diseases and disorders such as pain, pruritus and genetic disorders of skin keratinization. Its core technology is based on the design and development of small molecules modulating multiple targets or inhibiting the degradation of endogenous molecules exhibiting polypharmacology.

drug discovery and developmentmedicinal chemistryRNA sequencingsmall molecule design and development

DirectSeq Biosciences develops RNA sequencing technology, including its DSMX™-Seq platform, which directly sequences RNA molecules without cDNA conversion and identifies modified ribonucleotide bases. The company provides technology services for RNA therapeutics quality assurance, de-novo sequencing of RNA species, and biomarker discovery, built on advanced mass spectrometry and molecular biology.

Bioinformaticsde-novo sequencingdetection of modified basesdirect RNA sequencingLC-MS sequencing data acquisitionmass spectrometry

DNAe is a point-of-need next-generation sequencing company developing the LiDia-SEQ™ Platform, a direct-from-specimen diagnostic system that performs DNA sequencing on a microchip to provide rapid, actionable information to clinicians. Founded in 2003 as a spin-out from Imperial College London, it focuses on infectious disease diagnostics and antimicrobial resistance, including a bloodstream infection test. Headquartered in London, UK, with operations in Washington, DC, and a clinical diagnostic development site in San Diego, CA.

chemistryDNA sequencing on a microchipelectronic engineeringFluidicsgenomic analysissemiconductor sequencing

Dodds & Associates, established by David Dodds Ph.D., provides technical advice and management to start-up pharma, industrial biotech and renewable chemicals companies. D&A offers technical strategy, project management, due diligence, and expert witness services across organic synthesis, chiral chemistry, biocatalysis, synthetic biology, fermentation and strain development, and chem/bio process integration and scale-up.

biocatalysisbiotransformationschem/bio process integrationchiral chemistryexpert witnessfermentation and strain developmentorganic synthesisprocess development and scale-up

Expression Systems, an Advancion company headquartered in Davis, California, supplies and services the baculovirus, cell culture and bio-industrial markets with cell culture media formulations, cell lines, molecular tools, reagents, and contract manufacturing services. Founded in 1997, the company specializes in the baculovirus expression vector system (BEVS) and insect cell culture, offering products and services from gene optimization to protein purification.

baculovirus stock productionbaculovirus titeringcell culture media manufacturingcodon optimizationcontract manufacturinggene synthesisGMP manufacturingplasmid scale up and purificationprotein productionprotein purificationvector design and cloning