electrospinning

BioSurfaces develops medical devices, coatings, 3D tissue engineering scaffolds, and personal care products using its proprietary Bio-Spun® nanofiber technology. The company makes devices and coatings out of FDA-approved polymers via electrospinning, and its room-temperature electrospinning process allows drug loading into each fiber for sustained drug release. It is ISO 9001 QMS certified and collaborates with organizations including Takeda, NIH, and Corning.

3D tissue engineering scaffoldsdevice and coating manufacturingdrug loadingjoint development

Early Charm is a vertically integrated company that takes science from research institution licenses to commercial production, with R&D and manufacturing under one roof in Baltimore, Maryland. It serves both defense and commercial markets, developing dual-use products across advanced materials, bioengineering and biodefense, and sensors and analytics. The company reports 90 products in its pipeline and 11 fully commercial products, and is an SBIR/STTR awardee that is DCAA-compliant and SAM + CAGE registered.

3D bioprinting3D printingbiomanufacturingcastingcoatingcomputational drug designcustom material formulationData Analyticsoptical systemspoint-of-care diagnosticsprecision prototypingsonar-based monitoringspectroscopysurface engineering

ISURTEC (Innovative Surface Technologies, Inc.), founded in 2004 by Dr. Patrick Guire, is a Saint Paul, MN company specializing in surface modification and biofriendly coatings for medical devices. Its coatings have contributed to the safety and performance of over 100 medical devices. The company is certified to ISO 9001:2015 and offers contract research, laboratory services, feasibility studies, coating optimization, and custom coating development.

cell culturechemical synthesisdip coatingphotochemistrypolymer synthesisspray coatingsurface modificationUV curing

KLISBio is a medtech company developing implantable regenerative solutions powered by silk fibroin, combining biomaterials science, bioengineering, and surgical focus. Its product SILKBridge is a biointegrative nerve guide for surgical repair of peripheral nerve discontinuities, bioengineered from silk fibroin with a proprietary Tri-Layer architecture. KLISBio was founded in 2014 and is based in Bresso, Milan, Italy, with a U.S. office in Burlington, MA.

bioengineeringbiomaterials scienceimplantable medical device development