digital PCR (dPCR)

Accelevir is a Johns Hopkins University spinout bioanalytical CRO based in Baltimore, Maryland, operating a CAP-accredited, CLIA-certified and BSL-2+ laboratory. It provides molecular, genomic, immunology and bioanalytical testing services supporting cell and gene therapy, biologics and vaccine programs from preclinical studies through Phase 3 and long-term follow-up.

biobankingcell subset isolationcytotoxicity and killing assaysELISpotFlow Cytometryinfectious sample processing (BSL-2+)LC-MS/MSligand-binding assay (LBA)neutralization assaysnext-generation sequencing (NGS)PBMC processing and cryopreservationtargeted short- and long-read sequencingT-cell proliferation assays

Anvil Diagnostics Inc. is building next-generation molecular diagnostics for invasive infections. Its proprietary SKIP-Seq™ technology, originating from Rice University, delivers the speed of PCR with the breadth of sequencing on standard digital PCR hardware. Its MycoScan™ assay detects microbial cell-free DNA in plasma, targeting a 3-hour pan-fungal liquid biopsy, launched as a research use only (RUO) product.

algorithmic analysisassay developmentcell-free DNA detectioncomputational biologymolecular diagnostics

GT Molecular develops molecular detection technologies for cancer research and pathogen detection. The company designs ultra-sensitive digital PCR, qPCR, and next-generation sequencing assays, illicit drug detection tests, and end-to-end solutions for cancer genotyping and waterborne pathogen detection, including SARS-CoV-2 wastewater monitoring. It was awarded the CDC's NWSS Multi-Pathogen Assay Development Contract and was recognized by MIT Technology Review as the first lab to identify the SARS-CoV-2 UK variant signature in US sewersheds.

16S rRNA metagenomic sequencingbioinformatics analysiscustom NGS assay design and validationnext-generation sequencing (NGS)qPCR/RT-qPCRwastewater testing serviceswhole SARS-CoV-2 genome sequencing