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development of NLRP3 inflammasome antagonists

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1 development of nlrp3 inflammasome antagonists supplier across 1 states and provinces in 1 country. Profiles show capabilities, materials, certifications, and facility locations so you can compare shops and build a shortlist.

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Azome Therapeutics is a drug discovery company developing selective antagonists of the NLRP3 inflammasome, an inflammatory pathway involved in diseases such as acute lung injury, Acute Respiratory Distress Syndrome, Bronchopulmonary Dysplasia, systemic sepsis, acute liver and kidney injury, and pneumonia. Its lead candidate, AZM-152, is a RHAMM-derived antagonist that blocks an upstream priming signal in the aberrant activation of the NLRP3 inflammatory cascade. Initial indications target severe inflammatory pulmonary diseases with significant unmet need

drug discovery

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