computational design

Aspect Biosystems is a Canadian biotechnology company pioneering the development of bioprinted tissue therapeutics to transform how some of the most elusive diseases are treated. Its full-stack tissue therapeutic platform integrates AI-powered bioprinting technology, computational design tools, therapeutic cells, and advanced biomaterials to build allogeneic tissue therapeutics designed to replace, repair, or supplement biological function in the body.

biomanufacturingbioprintinglab automationmachine learningmicrofluidic printheadsregenerative medicinetissue engineering

BIMNYC is a multidisciplinary engineering, architecture, and construction support firm started in New York City, with offices in New York City and Fort Lauderdale, providing services nationwide. It specializes in Building Information Modeling (BIM), Virtual Design and Construction (VDC), and Digital Construction Management, supported by 3D laser scanning, reality capture, remote sensing, computational design, and digital asset management.

3D Laser Scanning3D modeling4D/5D simulationarchitectural designBIMConstruction Managementcost estimatingCPM schedulingdesign QCdigital fabricationdigital twindraftingground penetrating radarLiDARMobile Mappingrenderingroof leveling analysisshop drawingsVDC

BNIM is an employee-owned design company and the 2011 AIA National Architecture Firm Award winner. It designs and delivers beautiful, integrated environments to inspire change and enhance the human condition, with a practice focused on high-performance, human-purposed design and the green building movement.

architectural designconstruction related servicesinteriors and space planninglandscape designLEED certificationLiving Building certificationmaster planningNet Zero Energy performanceparametric explorationphysical prototypingpre-design analysisreal-time renderingstormwater managementvirtual and augmented reality

TRANSFORMING THE DRUG DISCOVERY PROCESS With our decades’ worth of drug discovery expertise and breakthrough computationalplatform, we are setting the pace for the next generation of drug discovery. No Guesses, Just Successes by Computational Design Learn More About Our Platform Denovicon’s mission is to bring better quality drugs to market faster and more affordably than existing methods. To do so, we’ve created a drug discovery platform that’s powered by AI, machine learning, generative therapeutic design, and physics-based approaches to achieve the best results. The platform effectively and swiftly triages trillions of molecules to identify high-quality leads (not simply hits) and transform them into optimized clinical candidates. In this way, the platform streamlines the overall drug discovery process leading to savings in time and money, while achieving higher rates of clinical.

AI/machine learning drug discoverygenerative therapeutic designmulti-objective optimizationphysics-based modelingsmall molecule drug discovery

TANDEM STUDIO is an architecture and design practice whose team includes registered architects Armando Rigau and Silvana Herrera. The studio describes architecture as a dialogic medium, working on projects ranging from abstract proposals to built structures, from the intimate scale of the home to interactions within a city. Their work includes buildings, interiors, master plans, products, graphics, and publications.

architectural designconstruction expertiserobotic fabricationsustainability and resiliencytechnical detailing

Epigen Biosciences is a pharmaceutical company discovering innovative, proprietary drugs to address unmet medical needs. It develops small-molecule compounds including an LPA1 receptor antagonist, selective sigma-1 receptor ligands, p70 S6 kinase inhibitors, and PAM-IIs, targeting conditions such as diabetic kidney disease, NASH/MASH, idiopathic pulmonary fibrosis, Alzheimer's disease, ALS, Fragile X syndrome, and stroke. The company combines medicinal chemistry and drug development expertise with academic collaborations.

ADME property assessmentdrug developmentfocused library synthesishit-to-lead and lead optimizationin silico drug discoverymedicinal chemistryscaffold-hoppingscreeningstrategic project management

Forma Systems builds the intelligence layer for structural optimization in industrialized construction. Spun out of MIT's Digital Structures Research Group, the company develops optimization software for the construction industry, starting with precast concrete. Its flagship product, Cimbra, is a rapid estimation tool for precast producers that evaluates existing products against project-specific requirements.

design generationphysics-based simulationpreliminary engineering automationstructural optimization